Our objective

Merging patient data with highly annotated genomics to individualize cancer care

Prostate cancer outcomes vary enormously, both because tumors differ and because access to the right treatment is unequal. The Weiner Research Lab pursues research that addresses both forces at once: the molecular biology that drives a particular cancer's behavior, and the structural factors that determine who gets the right treatment in time.

The lab works across imaging biomarkers, tumor genomics, focal therapy outcomes, and disparities research. Findings have appeared in European Urology, JAMA, Nature Communications, Cancer, and JCO Precision Oncology.

Lab at a glance

  • Cedars-Sinai Medical Center, Los Angeles
  • Adjunct UCLA David Geffen School of Medicine
  • Active CDMRP physician research funding
  • PCF Young Investigator, Movember TrueNTH Fellow
  • Trainees from medical, graduate, and undergraduate programs
  • Open to collaboration and trainee inquiries

Contact the lab

Focus areas

What we study

Intersecting research programs aimed at a single question: how do we get every man with prostate cancer the right care at the right time?

01

PSMA & molecular imaging

Funded in part by the Prostate Cancer Foundation Young Investigator Award, our work on the molecular correlates of prostate-specific membrane antigen helps explain who responds to PSMA-targeted imaging and therapy and who does not.

02

Focal therapy biomarkers

Genomic predictors that identify which men are best suited for HIFU and other focal approaches, so the right patients get less invasive treatment and the wrong ones do not.

03

Prostate cancer disparities

Why outcomes differ across racial and socioeconomic groups, including immune microenvironment differences, access to advanced imaging, and adherence to quality metrics globally.

04

Decision science

Patient-reported outcomes, prediction models for treatment regret, and tools that help patients and physicians make confident decisions when options look similar on paper.

05

Recurrence risk stratification

Defining who needs intensified therapy after surgery or radiation and who can be safely observed, drawing on systematic reviews and large international datasets.

06

Quality of care

International variation in adherence to evidence-based prostate cancer quality metrics, and how to close gaps where they exist.

Team

The people behind the work

Lab roster, summer 2026.

Adam B. Weiner, MD

Adam B. Weiner, MD

Principal Investigator

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Jiyoun Seo, PhD

Postdoctoral Fellow

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Pranav Movva, BS

Research Associate

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Camille Motchoffo Simo, BS

Intern

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Daniel Vega

Intern

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Bohang “Andy” Shou

Intern

Publications

Selected publications

The lab has contributed more than 80 peer-reviewed articles. Selected highlights below; the full list is on PubMed.

Unseen Scars

JAMA · 2025

Narrative essay on balancing family and career in surgical oncology.

Full publication list on PubMed → Google Scholar profile →

Clinical trials

Trials & studies

Cedars-Sinai is a major prostate cancer research center, and Dr. Weiner's patients have access to a broad portfolio of trials. Active studies span active surveillance optimization, novel imaging, focal therapy, and management of advanced disease.

Patients interested in trial participation: please mention it at your consultation. Researchers interested in collaboration: email Pranav.Movva@cshs.org.

Trainees

Join the lab

Postdocs, residents, medical students, and undergraduates are welcome. Trainees work on prostate cancer genomics, PSMA molecular imaging, focal therapy biomarkers, decision science, or disparities research, and most leave with first-author publications.

To apply, email Pranav.Movva@cshs.org with your CV and a paragraph about why this lab. Rolling admissions; we respond within one business day.

Funding

How the lab is supported

Active competitive grants from the field's leading funders, alongside institutional and philanthropic support.

Prostate Cancer
Foundation
Young Investigator Award · 2023
Movember
Foundation
TrueNTH Global Registry · 2025
Department of DefenseCDMRP Physician Research Award · 2024–2028
Cedars-Sinai
Cancer Center
Donna and Jesse Garber Award · 2026
Simon-Strauss
Foundation
Research Award · 2022
Anonymous
donors
Philanthropic gifts · 2024–2025

Research runs on philanthropy

Federal grants take years to land and rarely cover the riskiest, earliest-stage ideas, the ones most likely to shift the field. Philanthropy fills that gap. A gift of any size accelerates the work.

Support the research